Ampoule Filling And Sealing Machines
Overview of Ampoule Filling and Sealing Machine Series
Our ampoule filling and sealing machines are designed for accurate liquid filling and reliable flame sealing of glass ampoules used in pharmaceutical, cosmetic, laboratory, and chemical applications.
The models YH-APSM2S, YH-AmpouMiNi, and YH-APSM2 support 1–20 ml universal ampoule sizes by simply changing molds, making them ideal for laboratories, pilot production, and small to medium batch manufacturing.
Among them, YH-APSM2S and YH-AmpouMiNi use the pull sealing method, while YH-APSM2 adopts sweep-and-blow sealing, which produces a clean seal without glass waste tips.
For higher production requirements, the AGL Series offers greater output and is better suited for continuous filling and sealing of a single ampoule specification.
comparison of Ampoule Filling and sealing Machines
Choose the plan that suits you best. Click the image to watch the product video.
YH-AmpouMiNi
- PLC Control Panel, 1-20ml Universal
- Production Capacity: 600-900 pcs/h
- Automatic Bottle Feeding and Discharging
- Nitrogen flushing before and after filling, low residual oxygen
- Photoelectric sensing, no bottle, no filling
YH-APSM2S
- PLC Control Panel, 1-20ml Universal
- Production Capacity: ≥1200 pcs/h
- Nitrogen flushing before and after filling, low residual oxygen
- Photoelectric sensing, no bottle, no filling
YH-APSM2
- PLC Control Panel, 1-20ml Universal
- Production Capacity: ≥1200 pcs/h
- Nitrogen flushing before and after filling, low residual oxygen
- Photoelectric sensing, no bottle, no filling
- Sweep-and-blow sealing, no waste tip
AGL series
- PLC Control Panel
- Filling Range:1-2ml,5-10ml,20ml(Different specifications require different machines.)
- Production Capacity: 1800-11000 pcs/h
- Automatic Bottle Feeding and Discharging
- Nitrogen flushing before and after filling, low residual oxygen
- Photoelectric sensing, no bottle, no filling
Technical Comparison of Ampoule Filling and Sealing Machines
| Model | Ampoule Size | Sealing Method | Production Capacity | Application |
| YH-AmpouMiNi | 1–20 ml | Pull Sealing | 600–900 pcs/h | Laboratory / R&D |
| YH-APSM2S | 1–20 ml | Pull Sealing | ≥1200 pcs/h | Small production |
| YH-APSM2 | 1–20 ml | Sweep-and-Blow | ≥1200 pcs/h | No glass waste tip |
| AGL Series | 1–2 ml / 5–10 ml / 20 ml | Pull Sealing | 1800–11000 pcs/h | Large production |
AGL Series Ampoule Filling and Sealing Machine Specifications
| Model | Ampoule Size | Production Capacity | Voltage | Power |
| AGL-1 | 5–10 ml | 1800–2000 bottles/h | 220V | 0.37 kW |
| AGL-2 | 1–2 ml | 3600–4800 bottles/h | 220V | 0.37 kW |
| AGL-4 | 1–2 ml | 7000–9000 bottles/h | 220V | 0.55 kW |
| AGL-4 | 5–10 ml | 6000–8000 bottles/h | 220V | 0.55 kW |
| AGL-4 | 20 ml | 4000 bottles/h | 220V | 0.55 kW |
| AGL-6 | 1–2 ml | 9000–11000 bottles/h | 220V | 0.55 kW |
| AGL-6 | 5–10 ml | 9000 bottles/h | 220V | 0.55 kW |
| AGL-6 | 20 ml | 9000 bottles/h | 220V | 0.55 kW |
Applications of Ampoule Filling and Sealing Machines
Ampoule filling and sealing machines are widely used for liquid packaging in multiple industries:
Pharmaceutical injection production
Cosmetic serum packaging
Laboratory reagent filling
Chemical liquid packaging
Veterinary medicine production
Custom Ampoule Filling and Sealing Solutions
All machines support customization according to production requirements, including:
Different ampoule sizes
Filling volume adjustment
Nitrogen flushing system
Gas type selection
Voltage customization
Contact us for technical support, machine selection, and quotation.
Benefits Of Monoblock Filling Machine
Increased Efficiency
One of the biggest benefits of using a monoblock filling machine is increased efficiency. These machines are designed to automate the filling process, which reduces the time and manual labor required to fill containers. This not only saves time but also reduces the risk of human error and increases the consistency of the fill volume. As a result, you can fill more containers in less time, improving overall productivity and profitability.
Improved Accuracy
Another major benefit of monoblock filling machines is improved accuracy. These machines are equipped with precision metering systems that ensure consistent and accurate fill volumes. This helps reduce waste, improve product quality, and increase customer satisfactio
Enhanced Safety
Monoblock filling machines are designed with safety in mind. They are equipped with safety features such as automatic shut off valves and emergency stop buttons that help prevent accidents and injuries. These machines also reduce the risk of contamination by eliminating the need for manual handling of containers and liquids.
Lower Maintenance Costs
Monoblock filling machines are built to last, with high-quality materials and durable construction. This results in lower maintenance costs compared to manual filling methods and older, less reliable filling machines. Regular maintenance and cleaning are essential to keep your monoblock filling machine running smoothly and prolong its lifespan.
Increased Flexibility
Monoblock filling machines are highly flexible and can be adapted to fill a wide variety of liquids, container sizes, and fill volumes. This allows you to switch between products quickly and easily, improving overall efficiency and reducing downtime. Whether you're filling small bottles or large drums, a monoblock filling machine can help you meet your business needs.
Atmospheric pressure filling machine
It is filled by the weight of the liquid under atmospheric pressure. This type of filling machine is divided into two types: timed filling and constant volume filling. It is only suitable for filling low-viscosity and gas-free liquids such as milk, wine, etc.
Pressure filling machine
Filling is carried out at a pressure higher than atmospheric pressure, and can also be divided into two types: one is that the pressure in the liquid storage tank is equal to the pressure in the bottle, and the filling is performed by the liquid flowing into the bottle by its own weight. It is isobaric filling; the other is that the pressure in the liquid storage tank is higher than the pressure in the bottle, and the liquid flows into the bottle by the pressure difference. This method is mostly used in high-speed production lines.
Vacuum filling machine
Filling is carried out when the pressure in the bottle is lower than the atmospheric pressure. This kind of filling machine has simple structure, high efficiency, and can adapt to a wide range of viscosity of materials, such as oil, syrup, fruit wine, etc.
Oil filling machine
It can fill all kinds of oil products, such as edible oil, lubricating oil, peanut oil, soybean oil, etc. This type of filling machine is a filling machine specially developed for the filling of oil materials, which can realize flexible configuration of manual operation and unmanned operation.
Injection plug filling machine
This type of filling machine is suitable for food, daily chemical, oil and other special industries, and can fill various liquid and paste products, such as disinfectant, hand sanitizer, toothpaste, various cosmetics, etc.
Applications of Monoblock Filling Machine
Beverage Industry
Monoblock filling machines find extensive usage in the beverage industry for filling and packaging various products like water, soft drinks, juices, and alcoholic beverages. The ability to handle different bottle sizes and closure types makes them an ideal choice for beverage manufacturers.
Pharmaceutical Industry
The pharmaceutical industry requires strict compliance with hygiene and safety regulations. Monoblock filling machines with their advanced features like sterile filling and tamper-evident packaging provide a reliable and efficient solution for pharmaceutical companies.
Personal Care and Chemical Industry
Monoblock filling machines also cater to the personal care and chemical industries, where accurate filling, precise capping, and secure sealing are crucial. From shampoos and lotions to detergents and household chemicals, these machines ensure the highest level of quality and safety.

FAQ
Q: What about your installation service and sales service for machine?
A: 1.Guarantee is one year, we will supply spare parts or send engineers to your side if you need, we will give you service anytime, 24 hours, 7days.
2.We already prepare technical manual and operation video to show our customers, then it will be easy to install and use the machine.
3.It is free to train your worker in our factory or in your side by video.
Q: How are the products’ quality?
A: The products will be strictly inspected before shipment, so the quality could be guaranteed.
Q: What is the principle of filling machine?
A: The liquid filling machine operates on the principle of liquid pressure filling. When the pressure is high, the liquid flows into the bottle using its own weight. This process occurs when the pressure of the liquid reservoir matches the volume of air present in the bottle.
Q: How to measure and control the filling accuracy of the filling machine?
A: A filling machine's filling accuracy is defined as the size of the devia- tion between the actual filling value and the desired filling value. The deviation is found by check-weighing the gas cylinder after filling. In connection with carrousel filling this check is often performed on a separate scale (a check scale).
Q: You are a manufacture or a trading company?
A: We are truly a manufacture, can not only provide the high quality products with the best price, but also offer the best pre-sale service and after-service.
As one of the most professional ampoule filling and sealing machines manufacturers and suppliers in China, we're featured by quality products and competitive price. Please rest assured to buy cheap ampoule filling and sealing machines for sale here from our factory.
ampoule filler sealer, ampoule filling, glass ampoule sealer














